One in two hundredboys.A lifetime of answers.

Hypospadias affects roughly one in every two hundred male births, making it one of the most common congenital anomalies in pediatric urology. Its causes remain incompletely understood - genetic, hormonal, and environmental factors interact in ways that are still being mapped. The PG Lab studies the genomic architecture of hypospadias and related congenital genitourinary and gastrointestinal anomalies, using cohort genetics, exome sequencing, and population-based anthropometric nomograms to build an evidence base for how these conditions arise and how they should be treated. Our work moves between the operating table, the genome, and the published literature - translating surgical experience into reproducible, citable evidence that changes how children with congenital anomalies are counselled and treated.