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PG Lab
Pediatric Surgery - AIIMS New Delhi

§ What we do

Four threads.
One evidence base.

Our work moves between the operating table, the sequencer, and the published page - turning bedside observation into reproducible, citable evidence.

I
Thread 01

Pediatric Genomics & Precision Surgery

Focus: Hypospadias • Congenital Anomalies • Rare Diseases

We study the genetic basis of pediatric surgical disorders using whole-exome sequencing, transcriptomics, and epigenomic profiling. Our primary focus is hypospadias, where molecular findings are paired with detailed phenotyping to improve diagnosis, severity grading, and personalized management. We also investigate the underlying biology of pouch colon, biliary atresia, Wilms tumor, and other rare anomalies seen in surgical practice.

II
Thread 02

Artificial Intelligence & Bioinformatics

Focus: AI • Decision Support • Computational Biology

We build computational methods that accelerate biomedical discovery and support decisions at the bedside. This spans variant interpretation, machine learning, large language models for research, and predictive modeling. We are also developing open-source platforms that automate sequencing pipelines and literature discovery for clinicians and scientists alike.

III
Thread 03

Precision Nutrition, Psychology & Pediatric Genomics

Focus: Nutrigenomics • Psychogenomics • Developmental Health

We explore how genetic variation shapes metabolism, neurodevelopment, and psychological wellbeing in children with surgical disorders. By combining nutrigenomics, psychogenomics, and clinical biomarkers, we aim to understand each child’s biological response and support holistic, individualized long-term care.

IV
Thread 04

Evidence-Based Pediatric Surgery & Global Standards

Focus: Clinical Research • Reporting Guidelines • Population Health

We strengthen the evidence base of the specialty through systematic reviews, meta-analyses, and bibliometric analyses that trace how the literature itself is evolving. As contributors to international reporting guidelines, we help set global standards for how surgical research is documented, alongside validated nomograms and outcome measures that translate directly into everyday practice.