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Β§ Available Now

AI-Powered Evidence
Synthesis Platform

Conduct systematic reviews, meta-analyses, and omics evidence synthesis in one AI-assisted platform built for researchers, clinicians, and bioinformaticians.

Systematic ReviewsMeta-analysisOmics ResearchPRISMA Workflows
EvidenceFlow platform screenshot

3

Review Stages

10+

Statistical Analyses

PRISMA

2020 Ready

Integrates with the sources and standards you already use

PubMedCrossrefOpenAlexPRISMA 2020RISBibTeXCSVJSON

Β§ Features

Everything you need for modern evidence synthesis

From import to publication-ready output in one platform - no stitching tools together.

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Literature Screening

Conduct title, abstract, and full-text screening using a Rayyan-inspired workflow with conflict resolution and multi-reviewer collaboration.

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Meta-analysis Engine

Pool effect sizes and quantify heterogeneity in minutes, using fixed and random effects models with publication-ready forest and funnel plots.

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Omics Data Integration

Synthesize evidence across populations and studies with GWAS variant aggregation, weighted gene-level RNA-seq summaries, and chromosome-level Manhattan plots.

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AI-assisted Study Selection

Cut screening time by surfacing the most relevant studies first, with AI-powered relevance scoring against your research question.

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PRISMA Workflow

Stay reporting-compliant with zero manual bookkeeping, using automated PRISMA flow diagrams that track counts at every stage.

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Collaborative Reviews

Keep review teams in sync with role-based access, dual-reviewer screening, conflict detection, and a full audit trail.

Β§ See EvidenceFlow in Action

Built for how researchers actually work

Every screen is designed around real systematic review workflows.

Screening Interface
Screening

Screening Interface

Rayyan-style abstract viewer with AI relevance scores, include/exclude controls, conflict detection, and stage-by-stage progress.

  • βœ“AI relevance scoring
  • βœ“Three-stage screening queue
  • βœ“Conflict detection & resolution
  • βœ“Multi-reviewer support
Meta-analysis & Visualizations
Analysis

Meta-analysis & Visualizations

Forest plots, funnel plots, PRISMA flow diagrams, and omics Manhattan plots - all generated from your extracted study data.

  • βœ“Forest & funnel plots
  • βœ“PRISMA flow diagram
  • βœ“Omics variant aggregation
  • βœ“One-click PDF export

Β§ Workflow

From raw literature to synthesis in five steps

A structured pipeline that mirrors established systematic review methodology.

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Import

Upload PubMed XML, RIS, BibTeX, or CSV. Automatic duplicate detection removes redundant records.

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Screen

AI pre-scores relevance. Reviewers work through title, abstract, and full-text stages with conflict tracking.

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Extract

Structured clinical and omics forms capture effect sizes, genes, variants, populations, and risk of bias.

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Analyze

Fixed and random effects pooling, heterogeneity statistics, and GWAS / RNA-seq omics synthesis.

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Publish

Export publication-ready PDF reports, PRISMA diagrams, forest plots, and JSON data packages.

Β§ Who It’s For

Built for every stage of evidence work

Whether you’re running a single review or coordinating a department, EvidenceFlow fits the workflow.

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Clinical Researchers

Conduct PRISMA-compliant systematic reviews without switching between screening, extraction, and reporting tools.

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Bioinformaticians

Integrate GWAS, RNA-seq, and genomic datasets into your evidence synthesis alongside clinical literature.

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Medical Students

Complete dissertations and evidence syntheses faster with AI-assisted screening and structured data extraction.

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Universities

Run collaborative evidence reviews across departments with role-based access and a shared audit trail.

Open Science

Built on open science principles

EvidenceFlow is free and transparent - because good research infrastructure should be shared, not siloed.

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Transparent

All statistical methods are documented and auditable. Reproducible analyses with full parameter history.

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Reproducible

Export full data packages JSON, PDFs, and plots so every review step can be independently verified.

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Exportable

Your data is never locked in. Every project exports as CSV, JSON, and PDF, ready for reuse elsewhere.

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Open Standards

Import from PubMed, RIS, and BibTeX, and generate PRISMA 2020-compliant flow diagrams out of the box.

Β§ FAQ

Frequently asked questions

What is EvidenceFlow?+

EvidenceFlow is a free, AI-powered systematic review platform that automates literature screening, data extraction, PRISMA reporting, and meta-analysis for researchers and clinicians.

Is EvidenceFlow free to use?+

Yes. EvidenceFlow is completely free. Create an account and start your first systematic review immediately with no subscription required.

How does AI screening work in EvidenceFlow?+

EvidenceFlow uses local large language models (via Ollama) to screen studies against your PICO criteria and inclusion/exclusion criteria. It provides a decision (include/exclude/maybe), confidence score, and a one-sentence reason for each study.

What is the difference between EvidenceFlow and Rayyan or RevMan?+

EvidenceFlow combines the collaborative screening features of Rayyan with the meta-analysis capabilities of RevMan, and adds AI automation for screening and extraction, all in a single free platform.

Can EvidenceFlow generate a PRISMA flow diagram?+

Yes. EvidenceFlow automatically generates a PRISMA 2020 flow diagram based on your screening decisions and study counts, which can be exported as part of your PDF or Word report.

What file formats can I import into EvidenceFlow?+

EvidenceFlow supports RIS, BibTeX, CSV, and direct PubMed search import. You can also upload full-text PDFs for full-text screening.

Is EvidenceFlow open source?+

No, EvidenceFlow is not open source. It is completely free to use, and every project you create exports as CSV, JSON, or PDF, so your data is never locked in.

Can I collaborate with multiple reviewers?+

Yes. EvidenceFlow supports multi-reviewer projects with role-based access, dual-reviewer screening, conflict detection, and an audit trail of every decision.

Which statistical models are supported?+

EvidenceFlow's meta-analysis engine supports fixed and random effects models with pooled effect sizes, IΒ², Cochran's Q, and TauΒ² heterogeneity statistics, visualized as forest and funnel plots.

Does EvidenceFlow support PRISMA 2020?+

Yes. PRISMA 2020 flow diagrams are generated automatically from your screening decisions and can be exported as part of your PDF or Word report.

Can I export my project?+

Yes. You can export your PRISMA flow diagram, PDF report, Word document, or full CSV/JSON data package at any point in your project.

Is my research data private?+

Yes. Your projects and study data are private to your account and visible only to reviewers you explicitly invite to a project.

Can I use my own AI models?+

EvidenceFlow's AI screening runs on local large language models via Ollama, so no external API keys are required and your data never leaves the screening environment.

Who is EvidenceFlow designed for?+

EvidenceFlow is designed for clinical researchers, bioinformaticians, medical students, and universities running systematic reviews, meta-analyses, or omics evidence synthesis.

Does EvidenceFlow support omics research?+

Yes. EvidenceFlow integrates GWAS variant aggregation, RNA-seq gene-level summaries, and Manhattan plot visualization alongside your systematic review workflow.

Get Started

From literature search to publication in one platform

Create an account, import your references, and start AI-assisted screening with no configuration needed. EvidenceFlow is completely free.